Incazelo

I-TirzePatide yi-agOnist e-rustar receptor ye-glp-1 (i-glucagon-efana ne-peptide-1) ne-gip (i-anucose-encike ye-insulinotropic):

1. Ukuphathwa kwesisindo okungapheli

Indlela yokwenza isenzo:

Icindezela isifiso sokudla futhi inciphise ukuphuza ikhalori ngokusebenzisa uhlelo lwezinzwa oluphakathi, ngenkathi kuthuthukiswa izinkomba ze-metabolic.

Ukusebenza ngempumelelo:

Iziguli ezikhuluphele (BMI zikhulu kune- noma zilingana no-30): isilinganiso sokunciphisa isisindo se-15% -22% (umthamo omkhulu we-15 mg / ngesonto).

Okweqile + izinkinga (BMI ezinkulu kune noma zilingana no-27): Kuyasebenza nasezigulini ezine-hypertension kanye ne-dyslipidemia.

2. Thayipha isifo sikashukela

Indlela yokwenza isenzo:

Yenza kusebenze i-GLP-1 Receptors → Ukugqugquzela imfihlo ye-insulin, kuvimbela i-greacagon, futhi kubambezele ukuthulula i-gastric.

Yenza kusebenze ama-GIP Receptors → Thuthukisa ukuzwela kwe-insulin futhi unciphise ukunqwabelana kwamafutha.

Ukusebenza ngempumelelo:

Sinciphisa kakhulu i-HBA1C (i-hemoglobin egcwele i-glycosylated) (ukuncishiswa kwe-1.8% -2.4%).

Siza Ukunciphisa Isisindo (iziguli ezivivinyweni zemitholampilo zilahlekelwe ngesilinganiso esingu-5% -11% isisindo).

Inani labantu abasebenzayo:

Abantu abadala abanesifo sikashukela sohlobo 2 (kudingeka bahlanganise nokudla nokuzivocavoca).

3. Ukusetshenziswa okungaba khona ocwaningweni

I-Steatohepatitis engeyona yotshwala (NASS): Thuthukisa ukuvuvukala kwesibindi ne-fibrosis.

Ukuvikelwa kwenhliziyo: kunganciphisa ubungozi bezinhliziyo ezigulini ngesifo sikashukela sohlobo 2 (okufanayo nezidakamizwa ze-glp-1).

I-Polycystic Ovary Syndrome (PCOS): Thuthukisa ukungalingani kwama-hormone ngokunciphisa umzimba.

Ukuboniswa Komkhiqizo

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